Risk Factors and Clinical Outcomes of Neonatal Sepsis in Manado Tertiary Referral Hospital: A Single-center Study
نویسندگان
چکیده
BACKGROUND: Neonatal sepsis remains a major cause of morbidity and mortality among newborn infants, both term preterm. Even with effective treatment, the outcome is still uncertain, inflated health-care cost due to prolonged length stay in Intensive Care Unit. AIM: This study aimed evaluate risk factors their association clinical outcomes neonatal tertiary referral hospital Manado, Indonesia. METHODS: single-center retrospective cohort 365 subjects, conducted between January 2016 December 2018. Risk were divided into two groups: Neonatal-related maternal-related factors. Clinical analyzed survival (discharged or death) stay. Logistic regression, Mann–Whitney, Kruskal–Wallis test used statistical analysis. RESULTS: From all factors, highest rate was found neonates sclerema (83.1%), lowest without tachypnea (11.6%). Further multivariate analysis revealed associated mortality, such as (OR 4.94, 95% CI 2.257–10.841; p < 0.001) 34.47, 15.135‒78.509; 0.001). also reported several stay, very low birth weight (p 0.001), premature rupture membrane = 0.009), preterm gestational age non-hospital delivery location 0.013). CONCLUSION: In sepsis, presence significant for mortality. Meanwhile, membrane, weight, age,
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ژورنال
عنوان ژورنال: Open Access Macedonian Journal of Medical Sciences
سال: 2022
ISSN: ['1857-9655']
DOI: https://doi.org/10.3889/oamjms.2022.7993